Tobacco-free nicotine (TFN) is nicotine that is made in a lab instead of extracted from tobacco plants. It can also be called synthetic nicotine. Most of the nicotine used in eliquids was made by growing tobacco and extracting the nicotine from the plants. Although it is all nicotine, there are a few small differences. This is not to be confused with all 0% (zero) nicotine options. If you select a 0mg juice this is 0% nicotine and we have disposable vapes that are zero nicotine here